The estrogen-like compounds found in soy could help postmenopausal women get a better night’s sleep, according to a small study.

These compounds, isoflavones, have been tested for a number of menopausal symptoms as well as for treating health problems that become more common after menopause, such as high cholesterol, high blood sugar, and increased body fat. But so far, results have been disappointing.

Insomnia is very common in older women, Dr. Helena Hachul of the Universidade Federal de Sao Paolo and her colleagues write in the journal Menopause. Studies of whether hormone therapy helps with sleep problems have had mixed results, they add.

To investigate whether isoflavones might be beneficial, Hachul and her team randomly assigned 38 postmenopausal women with insomnia to take either 80 milligrams of the isoflavones or a placebo for four months. All of the study participants underwent polysomnography, which involves spending the night in a sleep lab so vital signs, sleep stages, and movements can be monitored; this is considered the gold standard for measuring sleep quality. Click here to read more about soy and women.

In the isoflavone group, average sleep efficiency (meaning the percentage of time that the women spent in bed that they were actually sleeping) went from 78 percent at the beginning of the study to 84 percent at the end; for the placebo group, sleep efficiency increased from 78 percent to 81 percent.

Among women given isoflavones, 90 percent reported “moderate or intense” insomnia at the beginning of the study, while 37 percent did after four months; in the placebo group, the percentages were 95 percent and 63 percent, respectively.

Read more: http://www.tehrantimes.com/index_View.asp?code=226233